TECHNOLOGY & PATENTS

Technology Beyond the Lab

We connect research outcomes to patents and commercialization for use in pharmaceutical evaluation and development.

Researcher conducting a cell-culture experiment

TRANSLATION

From insight
to application.

We extend findings from drug-delivery formulations, luminescent 3D tumoroids, and microfluidic evaluation platforms into intellectual property.

PATENTS & APPLICATIONS

Patent Portfolio

Navigation guidance system for visually impaired persons and control method thereof patent certificate image

Patent Certificate28

Granted2026

Navigation guidance system for visually impaired persons and control method thereof

Granted: 10-29925652026.07.14
Application: 10-2024-00312492024.03.05

InventorsDae Hwan Shin

Patent Details ↗

Automated manufacturing apparatus for nanoparticle-treated drug carriers patent certificate image

Patent Certificate27

Granted2026

Automated manufacturing apparatus for nanoparticle-treated drug carriers

Granted: 10-29843672026.06.25
Application: 10-2024-01913812024.12.19

InventorsDae Hwan Shin

Patent Details ↗

Microfluidic device for evaluating sustained anticancer activity and the EPR effect of nanoparticle drug formulations patent certificate image

Patent Certificate26

Granted2026

Microfluidic device for evaluating sustained anticancer activity and the EPR effect of nanoparticle drug formulations

Granted: 10-29421372026.03.17
Application: 10-2022-00982982022.08.08
PCT: PCT/KR2023/0100662023.07.14International Publication WO2024034888A1 · 2024.02.15

InventorsDae Hwan Shin · Moon-Seob Yoon · Jae-Min Lee

Patent Details ↗

TPGS-Soluplus micelles encapsulating olaparib and rapamycin and uses thereof patent certificate image

Patent Certificate25

Granted2026

TPGS-Soluplus micelles encapsulating olaparib and rapamycin and uses thereof

Granted: 10-29139922026.01.13
Application: 10-2023-01021942023.08.04

InventorsDae Hwan Shin · Yu-Bin Shin

Patent Details ↗

Pneumatically actuated feeding bottle patent certificate image

Patent Certificate24

Granted2026

Pneumatically actuated feeding bottle

Granted: 10-29111252026.01.07
Application: 10-2024-00374562024.03.18

InventorsDae Hwan Shin

Patent Details ↗

Method for producing luminescent gastric cancer cell-line tumoroids for continuous cytotoxicity analysis of anticancer agents patent certificate image

Patent Certificate23

Granted2026

Method for producing luminescent gastric cancer cell-line tumoroids for continuous cytotoxicity analysis of anticancer agents

Granted: 10-29104912026.01.06
Application: 10-2021-01489702021.11.02

InventorsDae Hwan Shin · Moon-Seob Yoon · Chae-Eun Jin

Patent Details ↗

Biometric-data-based medication management system and method patent application image

Patent Application22

Application2026

Biometric-data-based medication management system and method

Application: 10-2026-01512382026.08.12

InventorsDae Hwan Shin · Ji-Yeon Kim

Patent Details ↗

Dual-formulation container and aspirin-vitamin C combination drug using the same patent application image

Patent Application21

Application2026

Dual-formulation container and aspirin-vitamin C combination drug using the same

Application: 10-2026-01346152026.07.22

InventorsDae Hwan Shin

Patent Details ↗

Microneedle patch for corn removal patent application image

Patent Application20

Application2026

Microneedle patch for corn removal

Application: 10-2026-00539142026.03.25

InventorsDae Hwan Shin

Patent Details ↗

Bilayer tablet comprising a magnesium salt and a proton-pump inhibitor and method for preparing the same patent application image

Patent Application19

Application2026

Bilayer tablet comprising a magnesium salt and a proton-pump inhibitor and method for preparing the same

Application: 10-2026-00257492026.02.09

InventorsDae Hwan Shin

Patent Details ↗

Pharmaceutical composition for preventing or treating macular degeneration comprising thermosensitive PLGA-PEG-PLGA gel encapsulating apatinib or dexamethasone patent application image

Patent Application18

Application2026

Pharmaceutical composition for preventing or treating macular degeneration comprising thermosensitive PLGA-PEG-PLGA gel encapsulating apatinib or dexamethasone

Application: 10-2026-00181042026.01.29

InventorsDae Hwan Shin · Myeong-Gyun Yoo

Patent Details ↗

TPGS-Soluplus micelles encapsulating apatinib and etoposide and uses thereof patent application image

Patent Application17

Application2026

TPGS-Soluplus micelles encapsulating apatinib and etoposide and uses thereof

Application: 10-2026-00118932026.01.21

InventorsDae Hwan Shin · Myeong-Gyun Yoo

Patent Details ↗

Thermosensitive PLGA-PEG-PLGA hydrogel encapsulating gemcitabine and rapamycin and uses thereof patent certificate image

Patent Certificate16

Granted2025

Thermosensitive PLGA-PEG-PLGA hydrogel encapsulating gemcitabine and rapamycin and uses thereof

Granted: 10-28859552025.11.10
Application: 10-2022-01298072022.10.11

InventorsDae Hwan Shin · Seo-Yeon Kim

Patent Details ↗

Combination formulation of paclitaxel- and olaparib-loaded TPGS micelles with a pH-thermosensitive hydrogel for peritoneal metastasis and drug-resistant ovarian cancer patent application image

Patent Application15

Application2024

Combination formulation of paclitaxel- and olaparib-loaded TPGS micelles with a pH-thermosensitive hydrogel for peritoneal metastasis and drug-resistant ovarian cancer

Application: 10-2024-01861512024.12.13

InventorsDae Hwan Shin · Min-Jung Cho

Patent Details ↗

Poly(ethylene glycol)-poly(caprolactone) copolymer micelles encapsulating sorafenib and uses thereof patent application image

Patent Application14

Application2024

Poly(ethylene glycol)-poly(caprolactone) copolymer micelles encapsulating sorafenib and uses thereof

Application: 10-2024-00897822024.07.08

InventorsDae Hwan Shin · Chae-Eun Jin

Patent Details ↗

Polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft-copolymer micelles encapsulating osimertinib, etoposide, and docetaxel and uses thereof patent application image

Patent Application13

Application2024

Polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft-copolymer micelles encapsulating osimertinib, etoposide, and docetaxel and uses thereof

Application: 10-2024-00365822024.03.15

InventorsDae Hwan Shin · Hee-Ji Shin

Patent Details ↗

Drug evaluation method and system for simulating changes in blood concentration patent application image

Patent Application12

Application2023

Drug evaluation method and system for simulating changes in blood concentration

Application: 10-2023-01097442023.08.22
PCT: PCT/KR2024/0124992024.08.22International Publication WO2025042211A1 · 2025.02.27

InventorsDae Hwan Shin · Moon-Seob Yoon · Su-Jeong Kang

Patent Details ↗

Cut-to-dose tape formulation for pediatric medication patent application image

Patent Application11

Application2023

Cut-to-dose tape formulation for pediatric medication

Application: 10-2023-00877242023.07.06

InventorsDae Hwan Shin

Patent Details ↗

Poly(ethylene glycol)-poly(caprolactone) copolymer micelles encapsulating fenbendazole and rapamycin and uses thereof patent certificate image

Patent Certificate10

Granted2023

Poly(ethylene glycol)-poly(caprolactone) copolymer micelles encapsulating fenbendazole and rapamycin and uses thereof

Granted: 10-25846492023.09.26
Application: 10-2021-00917112021.07.13

InventorsDae Hwan Shin · Hee-Ji Shin · Min-Jung Cho

Patent Details ↗

Albumin nanoparticles encapsulating docetaxel and apatinib and uses thereof patent certificate image

Patent Certificate09

Granted2023

Albumin nanoparticles encapsulating docetaxel and apatinib and uses thereof

Granted: 10-25765592023.09.05
Application: 10-2021-00768402021.06.14

InventorsDae Hwan Shin · Yu-Jin Lee · Seo-Yeon Kim

Patent Details ↗

Poly(ethylene glycol)-poly(caprolactone) copolymer micelles encapsulating docetaxel and osthole and uses thereof patent certificate image

Patent Certificate08

Granted2023

Poly(ethylene glycol)-poly(caprolactone) copolymer micelles encapsulating docetaxel and osthole and uses thereof

Granted: 10-24909402023.01.17
Application: 10-2021-00027942021.01.08

InventorsDae Hwan Shin · Min-Jung Cho

Patent Details ↗

pH-sensitive poly(ethylene glycol)-poly(caprolactone) copolymer micelles encapsulating paclitaxel, etoposide, and rapamycin and uses thereof patent certificate image

Patent Certificate07

Registration2026

pH-sensitive poly(ethylene glycol)-poly(caprolactone) copolymer micelles encapsulating paclitaxel, etoposide, and rapamycin and uses thereof

Registration: 10-30201502026.09.10
Application: 10-2022-01298082022.10.11

InventorsDae Hwan Shin · Min-Jung Cho

Patent Details ↗

Fenbendazole-solubilizing composition and uses thereof patent certificate image

Patent Certificate06

Granted2022

Fenbendazole-solubilizing composition and uses thereof

Granted: 10-24554232022.10.12
Application: 10-2020-01520442020.11.13

InventorsDae Hwan Shin · Ik-Seop Jin

Patent Details ↗

Solubilizing composition for a fingolimod derivative and uses thereof patent certificate image

Patent Certificate05

Granted2022

Solubilizing composition for a fingolimod derivative and uses thereof

Granted: 10-23773342022.03.17
Application: 10-2020-01208772020.09.18

InventorsDae Hwan Shin · Moon-Seob Yoon

Patent Details ↗

Alpinumisoflavone-solubilizing composition and uses thereof patent certificate image

Patent Certificate04

Granted2021

Alpinumisoflavone-solubilizing composition and uses thereof

Granted: 10-23007372021.09.06
Application: 10-2019-01757152019.12.26

InventorsDae Hwan Shin · Min-Jung Cho

Patent Details ↗

Nanomicelles containing paclitaxel and alpinumisoflavone, preparation method, and uses thereof patent certificate image

Patent Certificate03

Granted2021

Nanomicelles containing paclitaxel and alpinumisoflavone, preparation method, and uses thereof

Granted: 10-22636062021.06.04
Application: 10-2020-00163942020.02.11

InventorsDae Hwan Shin · Yu-Jin Lee

Patent Details ↗

Disinfecting pen for touching buttons patent certificate image

Patent Certificate02

Granted2020

Disinfecting pen for touching buttons

Granted: 10-21852072020.11.25
Application: 10-2020-00492002020.04.23

InventorsDae Hwan Shin

Patent Details ↗

Pharmaceutical composition for preventing or treating glioblastoma comprising gemcitabine-loaded immunoliposomes and bevacizumab patent certificate image

Patent Certificate01

Granted2017

Pharmaceutical composition for preventing or treating glioblastoma comprising gemcitabine-loaded immunoliposomes and bevacizumab

Granted: 10-17352842017.05.08
Application: 10-2016-00223162016.02.25

InventorsJin-Seok Kim · Dae Hwan Shin

Patent Details ↗

KARE · INDUSTRY CONNECTION

Commercializing a 3D Biomimetic Research Platform

The lab's 3D biomimetic evaluation technology is being extended into research services through industry-academic collaboration with Korea Animal Replacement Experiment Inc.Visit KARE ↗

Technology Beyond the Lab

From insightto application.

Patent Portfolio

Navigation guidance system for visually impaired persons and control method thereof

Automated manufacturing apparatus for nanoparticle-treated drug carriers

Microfluidic device for evaluating sustained anticancer activity and the EPR effect of nanoparticle drug formulations

TPGS-Soluplus micelles encapsulating olaparib and rapamycin and uses thereof

Pneumatically actuated feeding bottle

Method for producing luminescent gastric cancer cell-line tumoroids for continuous cytotoxicity analysis of anticancer agents

Biometric-data-based medication management system and method

Dual-formulation container and aspirin-vitamin C combination drug using the same

Microneedle patch for corn removal

Bilayer tablet comprising a magnesium salt and a proton-pump inhibitor and method for preparing the same

Pharmaceutical composition for preventing or treating macular degeneration comprising thermosensitive PLGA-PEG-PLGA gel encapsulating apatinib or dexamethasone

TPGS-Soluplus micelles encapsulating apatinib and etoposide and uses thereof

Thermosensitive PLGA-PEG-PLGA hydrogel encapsulating gemcitabine and rapamycin and uses thereof

Combination formulation of paclitaxel- and olaparib-loaded TPGS micelles with a pH-thermosensitive hydrogel for peritoneal metastasis and drug-resistant ovarian cancer

Poly(ethylene glycol)-poly(caprolactone) copolymer micelles encapsulating sorafenib and uses thereof

Polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft-copolymer micelles encapsulating osimertinib, etoposide, and docetaxel and uses thereof

Drug evaluation method and system for simulating changes in blood concentration

Cut-to-dose tape formulation for pediatric medication

Poly(ethylene glycol)-poly(caprolactone) copolymer micelles encapsulating fenbendazole and rapamycin and uses thereof

Albumin nanoparticles encapsulating docetaxel and apatinib and uses thereof

Poly(ethylene glycol)-poly(caprolactone) copolymer micelles encapsulating docetaxel and osthole and uses thereof

pH-sensitive poly(ethylene glycol)-poly(caprolactone) copolymer micelles encapsulating paclitaxel, etoposide, and rapamycin and uses thereof

Fenbendazole-solubilizing composition and uses thereof

Solubilizing composition for a fingolimod derivative and uses thereof

Alpinumisoflavone-solubilizing composition and uses thereof

Nanomicelles containing paclitaxel and alpinumisoflavone, preparation method, and uses thereof

Disinfecting pen for touching buttons

Pharmaceutical composition for preventing or treating glioblastoma comprising gemcitabine-loaded immunoliposomes and bevacizumab

Commercializing a 3D Biomimetic Research Platform

From insight
to application.